By Oladapo Ashiru
Early diagnosis by rectal examination at the doctor’s clinic can be very helpful in detecting prostate enlargement. More recently, a very sensitive test has been put in place for early detection of prostate enlargement by checking the level of a substance called Prostate Specific Antigen, which can give an indication of an overactive prostate.
High PSA levels might give a clue to likely prostate problems. It is recommended that one should have a medical examination annually to rule out prostate enlargement. Men are advised to take multivitamins that contain extra zinc along with Vitamins C, D and E, which are rich in antioxidants. Zinc is good for the prostrate because it is required in the normal functioning of the gland. Prostate secretion contains a high quantity of zinc. Zinc removes the toxin cadmium and also inhibits the secretion of 5-alpha reductase, which is a toxin. A clinical trial dose of 150mg of zinc daily for two months and subsequent 50-150mg per day has recorded a 74 per cent success in treating abnormal enlargement of the prostate.
Prostate cancer patients have low levels of Lycopene. Lycopene is one of the major carotenoids present in light yellow or deep red fruits and aid the absorption of Vitamin A, which is a powerful antioxidant. Lycopene is found in fresh tomatoes, tomato sauces and pastes as well as in watermelon.There is a growing amount of data supporting the claim that a diet rich in lycopene may help to prevent various chronic diseases, including cancers of the lungs and prostrate. Other non-prescription alternatives for benign prostrate enlargements are the mineral saw palmetto, a handful of pumpkin seeds chewed once a week, drinking plenty of water and eating a diet high in fibre.
As men grow older, they can actively take care of their health and safeguard against prostate cancer by eating a diet high in fibre. Fibre binds to testosterone and eliminates it from the system.
They can also reduce the cholesterol in their diets by reducing saturated fatty acid found in palm oil and groundnut. Instead, men should increase their consumption of Omega 3 essential fatty acids from such sources as cod liver oil, geisha, mackerel and when available, salmon.
Garlic, onions and cabbage have also been known to be beneficial. Elderly people should also go to bed early the same time each night as irregular sleep disturbs the melatonin, a hormone produced by the pineal gland in the brain, which controls our sleeping hours or circadian rhythm and this affects the androgen receptors of the prostate gland.
If the prostate is enlarged, doctors can prescribe drugs to reduce its size. They are referred to as Anti-androgens. Such anti-androgens like flutamide, nilutamide and bicalumide have also been prescribed to reduce the circulating level of testosterone.
The most recent addition is the use of hormone therapy called LHRH analogue, like Lupron depot, to reduce the size of the enlargement and treat some advance cases of prostate cancer. A new report published in October 26, 2015 gave an insight to some genetic role in prostate cancer. Prostate cancer is one of the most common cancers affecting men
It is not yet possible to accurately distinguish between ‘indolent’ prostate cancers, which need little, if any treatment, and ‘aggressive’ cancers that require intensive intervention. A new research published in Oncotarget by a multi-disciplinary team at Nottingham, Weill Cornell Medical School, Lund University in Sweden and Copenhagen University in Denmark, has identified a significant gene called miR137 that is switched off in prostate cancer cells.
Lead researcher at Nottingham, Dr. Nigel Mongan said, “With many men continuing to die from metastatic prostate cancer, there is an urgent need to develop new ways to enable the early identification of aggressive cancers when such tumours remain localised within the prostate gland when surgery is most effective. We also need to make sure that men with indolent diseases do not receive unnecessary treatment which can lead to urinary continence and sexual dysfunction.”
The researchers studied the role of androgens in prostate cancer. Androgens are important signalling molecules, which play an essential role in men’s health by driving the development, repair and regeneration of the prostate and other tissues. However defective and amplified androgen signalling can trigger prostate cancer and its spread.
For this reason, many available prostate cancer treatments are aimed at blocking androgen signalling. However, resistance to such therapies is a major clinical challenge. The gene identified by the team, called miR137, is switched off in prostate cancer cells. It functions like a ‘dimmer switch’ in normal cells to reduce androgen signalling.In prostate cancer, where miR137 is switched off, the effect of androgen signalling is increased. Therefore, the loss of miR137 leads to enhanced androgen signalling which contributes to prostate cancer initiation and progression. The study has also identified many new potential targets for the next generation of drugs to treat prostate cancer. New research is now underway in the Mongan’s laboratory at Nottingham to test the effect of various pharmacological treatments in pre-clinical prostate cancer studies.
Mart-Life Detox clinic has recorded many success stories in men within the age range of 65-75 years diagnosed with prostate cancer. Modern Mayr Medicine has been able to help them to get rid of environmental toxins within 10 days of therapy and improve their feeling of well-being. This therapy, used concurrently with monthly depot injection of LHRH agonist, has helped to significantly lower the PSA level to normal or near normal by the end of the third monthly injection.